Research Interests and
My current research interests are focused on the study of
fish disease and environmentally related topics in the St.
Marys River Ecosystem. In particular, our laboratory is
investigating the thiamine (vitamin B1) deficiency in Great
Lakes Salmonids called EMS. This deficiency, often termed EMS,
is caused by the presence of thiaminase in forage fish such as
the alewife and our efforts are focused on the purification
and thorough biochemical investigation of this enzyme.
Other activities include environmental chemistry related to
the St. Marys river.
Opportunities for senior thesis and summer employment can
be discussed by contacting me at the phone or email listed
- R. Marshall Werner, Leonard M. Williams, and
Jeffery T. Davis, "The C-Glycosyl Analog of an N-Linked
Glycoamino Acid." Tetrahedron Letters, 1998, 39,
- James K. Coward, Tong Xu, Barbara S. Gibbs, R.
Marshall Werner, and Jeffery T. Davis,
"Oligosaccharyltransferase: Recent research on catalysis and
ligand binding." FASEB Journal, 1999, 13, A1539,
- R. Marshall Werner, Yu-Lin Jaing, Russell G.
Gordely, G. Jayashree Jagedeesh, Jane E. Ladner, Gaoyi Xiao,
Maria Tordova, Gary Gilliland, and James T. Stivers,
"Stressing-Out DNA? The contribution of
Serine-Phosphodiester Interactions In Catalysis by Uracil
DNA Glycosylase." Biochemistry, 2000, 39,
- R. Marshall Werner and James T. Stivers, "Kinetic
Isotope Effect Studies of the Reaction Catalyzed by Uracil
DNA Glycosylase: Evidence for An Oxocarbenium Ion-Uracil
Anion Intermediate." Biochemistry, 2000, 14054-14064.