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R. Marshall Werner

Associate Professor of Chemistry & Environmental Science

314 Crawford Hall
Lake Superior State University
650 W. Easterday Ave.
Sault Ste. Marie, MI 49783
(906) 635-2281 phone

B.S. Biology, Cornell University, 1993
Ph.D. Bioorganic Chemistry, University of Maryland College Park, 1998

Area of Specialty:
Organic Chemistry
Environmental Chemistry

Research Interests and Opportunities

My current research interests are focused on the study of fish disease and environmentally related topics in the St. Marys River Ecosystem. In particular, our laboratory is investigating the thiamine (vitamin B1) deficiency in Great Lakes Salmonids called EMS. This deficiency, often termed EMS, is caused by the presence of thiaminase in forage fish such as the alewife and our efforts are focused on the purification and thorough biochemical investigation of this enzyme.

Other activities include environmental chemistry related to the St. Marys river.

Opportunities for senior thesis and summer employment can be discussed by contacting me at the phone or email listed above.

Recent Publications

  • R. Marshall Werner, Leonard M. Williams, and Jeffery T. Davis, "The C-Glycosyl Analog of an N-Linked Glycoamino Acid." Tetrahedron Letters, 1998, 39, 9135-9138.

  • James K. Coward, Tong Xu, Barbara S. Gibbs, R. Marshall Werner, and Jeffery T. Davis, "Oligosaccharyltransferase: Recent research on catalysis and ligand binding." FASEB Journal, 1999, 13, A1539, suppl. S.

  • R. Marshall Werner, Yu-Lin Jaing, Russell G. Gordely, G. Jayashree Jagedeesh, Jane E. Ladner, Gaoyi Xiao, Maria Tordova, Gary Gilliland, and James T. Stivers, "Stressing-Out DNA? The contribution of Serine-Phosphodiester Interactions In Catalysis by Uracil DNA Glycosylase." Biochemistry, 2000, 39, 12585-12594.

  • R. Marshall Werner and James T. Stivers, "Kinetic Isotope Effect Studies of the Reaction Catalyzed by Uracil DNA Glycosylase: Evidence for An Oxocarbenium Ion-Uracil Anion Intermediate." Biochemistry, 2000, 14054-14064.
Department of Chemistry & Environmental Science - Lake Superior State University
650 W. Easterday Ave., Sault Ste. Marie, MI  49783
Phone:(906) 635-2267  Fax:(906) 635-2266
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Page content last revised on: 20 January 2004
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